Ablation of the Cardiac-Specific Gene Leucine-Rich Repeat Containing 10 (Lrrc10) Results in Dilated Cardiomyopathy

Leucine-rich repeat containing 10 (LRRC10) is a cardiac-specific protein exclusively expressed in embryonic and adult cardiomyocytes. However, the role of LRRC10 in mammalian cardiac physiology remains unknown. To determine if LRRC10 is critical for cardiac function, Lrrc10-null (Lrrc10(−/−)) mice w...

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Detalles Bibliográficos
Autores principales: Brody, Matthew J., Hacker, Timothy A., Patel, Jitandrakumar R., Feng, Li, Sadoshima, Junichi, Tevosian, Sergei G., Balijepalli, Ravi C., Moss, Richard L., Lee, Youngsook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517560/
https://www.ncbi.nlm.nih.gov/pubmed/23236519
http://dx.doi.org/10.1371/journal.pone.0051621

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