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Depletion of Endothelial or Smooth Muscle Cell-Specific Angiotensin II Type 1a Receptors Does Not Influence Aortic Aneurysms or Atherosclerosis in LDL Receptor Deficient Mice

BACKGROUND: Whole body genetic deletion of AT1a receptors in mice uniformly reduces hypercholesterolemia and angiotensin II-(AngII) induced atherosclerosis and abdominal aortic aneurysms (AAAs). However, the role of AT1a receptor stimulation of principal cell types resident in the arterial wall rema...

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Detalles Bibliográficos
Autores principales:	Rateri, Debra L., Moorleghen, Jessica J., Knight, Victoria, Balakrishnan, Anju, Howatt, Deborah A., Cassis, Lisa A., Daugherty, Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517567/ https://www.ncbi.nlm.nih.gov/pubmed/23236507 http://dx.doi.org/10.1371/journal.pone.0051483

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