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A Cell Permeable NPE Caged ADP-Ribose for Studying TRPM2
Transient potential receptor melastatin-2 (TRPM2) is a non-selective Ca(2+)-permeable cation channel of the TRPM channel subfamily and is mainly activated by intracellular adenosine diphosphate ribose (ADPR). Here we synthesized a 1-(2-nitrophenyl)ethyl caged ADPR (NPE-ADPR) and found that uncaging...
Autores principales: | Yu, Peilin, Wang, Qian, Zhang, Li-He, Lee, Hon-Cheung, Zhang, Liangren, Yue, Jianbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517590/ https://www.ncbi.nlm.nih.gov/pubmed/23236422 http://dx.doi.org/10.1371/journal.pone.0051028 |
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