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ΔNp73 Enhances Promoter Activity of TGF-β Induced Genes
The p53 homolog p73 is frequently overexpressed in cancers. Especially the transactivation domain truncated isoform ΔNp73 has oncogenic properties and its upregulation is associated with poor patient survival. It has been shown that ΔNp73 has an inhibitory effect on the transactivation capacity of p...
Autores principales: | Niemantsverdriet, Maarten, Nagle, Peter, Chiu, Roland K., Langendijk, Johannes A., Kampinga, Harm H., Coppes, Robert P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517593/ https://www.ncbi.nlm.nih.gov/pubmed/23236396 http://dx.doi.org/10.1371/journal.pone.0050815 |
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