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Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations

Meta-analyses of European populations has successfully identified genetic variants in over 100 loci associated with lipid levels, but our knowledge in other ethnicities remains limited. To address this, we performed dense genotyping of ∼2,000 candidate genes in 7,657 African Americans, 1,315 Hispani...

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Detalles Bibliográficos
Autores principales: Elbers, Clara C., Guo, Yiran, Tragante, Vinicius, van Iperen, Erik P. A., Lanktree, Matthew B., Castillo, Berta Almoguera, Chen, Fang, Yanek, Lisa R., Wojczynski, Mary K., Li, Yun R., Ferwerda, Bart, Ballantyne, Christie M., Buxbaum, Sarah G., Chen, Yii-Der Ida, Chen, Wei-Min, Cupples, L. Adrienne, Cushman, Mary, Duan, Yanan, Duggan, David, Evans, Michele K., Fernandes, Jyotika K., Fornage, Myriam, Garcia, Melissa, Garvey, W. Timothy, Glazer, Nicole, Gomez, Felicia, Harris, Tamara B., Halder, Indrani, Howard, Virginia J., Keller, Margaux F., Kamboh, M. Ilyas, Kooperberg, Charles, Kritchevsky, Stephen B., LaCroix, Andrea, Liu, Kiang, Liu, Yongmei, Musunuru, Kiran, Newman, Anne B., Onland-Moret, N. Charlotte, Ordovas, Jose, Peter, Inga, Post, Wendy, Redline, Susan, Reis, Steven E., Saxena, Richa, Schreiner, Pamela J., Volcik, Kelly A., Wang, Xingbin, Yusuf, Salim, Zonderland, Alan B., Anand, Sonia S., Becker, Diane M., Psaty, Bruce, Rader, Daniel J., Reiner, Alex P., Rich, Stephen S., Rotter, Jerome I., Sale, Michèle M., Tsai, Michael Y., Borecki, Ingrid B., Hegele, Robert A., Kathiresan, Sekar, Nalls, Michael A., Taylor, Herman A., Hakonarson, Hakon, Sivapalaratnam, Suthesh, Asselbergs, Folkert W., Drenos, Fotios, Wilson, James G., Keating, Brendan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517599/
https://www.ncbi.nlm.nih.gov/pubmed/23236364
http://dx.doi.org/10.1371/journal.pone.0050198