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Preventive Treatment with Methylprednisolone Paradoxically Exacerbates Experimental Autoimmune Encephalomyelitis

Glucocorticoids (GCs) represent the standard treatment for acute disease bouts in multiple sclerosis (MS) patients, for which methylprednisolone (MP) pulse therapy is the most frequently used protocol. Here, we compared the efficacy of therapeutic and preventive MP application in MOG(35-55)-induced...

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Detalles Bibliográficos
Autores principales: Wüst, Simone, van den Brandt, Jens, Reichardt, Holger M., Lühder, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517859/
https://www.ncbi.nlm.nih.gov/pubmed/23251153
http://dx.doi.org/10.1155/2012/417017