Cargando…
The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats
Although antioxidants have been repeatedly tested in animal models and clinical studies, there is no evidence that antioxidants reduce already developed age-related decline. Recently we demonstrated that mitochondria-targeted antioxidant 10-(6'-plastoquinonyl) decyltriphenylphosphonium (SkQ1) d...
Autores principales: | Kolosova, Nataliya G., Stefanova, Natalia A., Muraleva, Natalia A., Skulachev, Vladimir P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517939/ https://www.ncbi.nlm.nih.gov/pubmed/23104863 |
Ejemplares similares
-
SkQ1 Suppresses the p38 MAPK Signaling Pathway Involved in Alzheimer’s Disease-Like Pathology in OXYS Rats
por: Muraleva, Natalia A., et al.
Publicado: (2020) -
Mitochondria-targeted antioxidant SkQ1 inhibits age-dependent
involution of the thymus in normal and senescence-prone rats
por: Obukhova, Lidia A., et al.
Publicado: (2009) -
Suppression of Alzheimer's Disease-Like Pathology Progression by Mitochondria-Targeted Antioxidant SkQ1: A Transcriptome Profiling Study
por: Stefanova, Natalia A., et al.
Publicado: (2019) -
Suppression of AMD-Like Pathology by Mitochondria-Targeted Antioxidant SkQ1 Is Associated with a Decrease in the Accumulation of Amyloid β and in mTOR Activity
por: Muraleva, Natalia A., et al.
Publicado: (2019) -
Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents
por: Anisimov, Vladimir N., et al.
Publicado: (2011)