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Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine
Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel re...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518098/ https://www.ncbi.nlm.nih.gov/pubmed/23243542 http://dx.doi.org/10.1155/2012/412412 |
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author | Bajorek, Sarah Basaldua, Roel McGoogan, Katherine Miller, Charla Sussman, Craig B. |
author_facet | Bajorek, Sarah Basaldua, Roel McGoogan, Katherine Miller, Charla Sussman, Craig B. |
author_sort | Bajorek, Sarah |
collection | PubMed |
description | Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel rest and intravenous fluids, is the most common treatment regimen for uncomplicated GLB. Surgical measures are reserved for the rare complications of obstruction and/or perforation. Although limited, utilization of the protein-cleaving enzyme N-acetylcysteine has been described for the disintegration of GLB in toddlers. In this paper, we discuss the first documented use of N-acetylcysteine for a neonatal GLB. Supporting literature, the infant's unusual presentation, and details of the treatment regimen are discussed. |
format | Online Article Text |
id | pubmed-3518098 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-35180982012-12-14 Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine Bajorek, Sarah Basaldua, Roel McGoogan, Katherine Miller, Charla Sussman, Craig B. Case Rep Pediatr Case Report Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel rest and intravenous fluids, is the most common treatment regimen for uncomplicated GLB. Surgical measures are reserved for the rare complications of obstruction and/or perforation. Although limited, utilization of the protein-cleaving enzyme N-acetylcysteine has been described for the disintegration of GLB in toddlers. In this paper, we discuss the first documented use of N-acetylcysteine for a neonatal GLB. Supporting literature, the infant's unusual presentation, and details of the treatment regimen are discussed. Hindawi Publishing Corporation 2012 2012-12-02 /pmc/articles/PMC3518098/ /pubmed/23243542 http://dx.doi.org/10.1155/2012/412412 Text en Copyright © 2012 Sarah Bajorek et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Bajorek, Sarah Basaldua, Roel McGoogan, Katherine Miller, Charla Sussman, Craig B. Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine |
title | Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine |
title_full | Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine |
title_fullStr | Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine |
title_full_unstemmed | Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine |
title_short | Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine |
title_sort | neonatal gastric lactobezoar: management with n-acetylcysteine |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518098/ https://www.ncbi.nlm.nih.gov/pubmed/23243542 http://dx.doi.org/10.1155/2012/412412 |
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