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Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine

Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel re...

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Autores principales: Bajorek, Sarah, Basaldua, Roel, McGoogan, Katherine, Miller, Charla, Sussman, Craig B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518098/
https://www.ncbi.nlm.nih.gov/pubmed/23243542
http://dx.doi.org/10.1155/2012/412412
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author Bajorek, Sarah
Basaldua, Roel
McGoogan, Katherine
Miller, Charla
Sussman, Craig B.
author_facet Bajorek, Sarah
Basaldua, Roel
McGoogan, Katherine
Miller, Charla
Sussman, Craig B.
author_sort Bajorek, Sarah
collection PubMed
description Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel rest and intravenous fluids, is the most common treatment regimen for uncomplicated GLB. Surgical measures are reserved for the rare complications of obstruction and/or perforation. Although limited, utilization of the protein-cleaving enzyme N-acetylcysteine has been described for the disintegration of GLB in toddlers. In this paper, we discuss the first documented use of N-acetylcysteine for a neonatal GLB. Supporting literature, the infant's unusual presentation, and details of the treatment regimen are discussed.
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spelling pubmed-35180982012-12-14 Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine Bajorek, Sarah Basaldua, Roel McGoogan, Katherine Miller, Charla Sussman, Craig B. Case Rep Pediatr Case Report Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel rest and intravenous fluids, is the most common treatment regimen for uncomplicated GLB. Surgical measures are reserved for the rare complications of obstruction and/or perforation. Although limited, utilization of the protein-cleaving enzyme N-acetylcysteine has been described for the disintegration of GLB in toddlers. In this paper, we discuss the first documented use of N-acetylcysteine for a neonatal GLB. Supporting literature, the infant's unusual presentation, and details of the treatment regimen are discussed. Hindawi Publishing Corporation 2012 2012-12-02 /pmc/articles/PMC3518098/ /pubmed/23243542 http://dx.doi.org/10.1155/2012/412412 Text en Copyright © 2012 Sarah Bajorek et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bajorek, Sarah
Basaldua, Roel
McGoogan, Katherine
Miller, Charla
Sussman, Craig B.
Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine
title Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine
title_full Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine
title_fullStr Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine
title_full_unstemmed Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine
title_short Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine
title_sort neonatal gastric lactobezoar: management with n-acetylcysteine
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518098/
https://www.ncbi.nlm.nih.gov/pubmed/23243542
http://dx.doi.org/10.1155/2012/412412
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