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Downregulation of Cyclophilin A by siRNA diminishes non-small cell lung cancer cell growth and metastasis via the regulation of matrix metallopeptidase 9

BACKGROUND: Cyclophilin A (CypA) is a cytosolic protein possessing peptidyl-prolyl isomerase activity that was recently reported to be overexpressed in several cancers. Here, we explored the biology and molecular mechanism of CypA in non-small cell lung cancer (NSCLC). METHODS: The expression of Cyp...

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Detalles Bibliográficos
Autores principales:	Qian, Zhe, Zhao, Xiaoting, Jiang, Mei, Jia, Wenyun, Zhang, Chunyan, Wang, Yue, Li, Baolan, Yue, Wentao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518206/ https://www.ncbi.nlm.nih.gov/pubmed/23031673 http://dx.doi.org/10.1186/1471-2407-12-442

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