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Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex
The bacterial ATPase SecA and protein channel complex SecYEG form the core of an essential protein translocation machinery. The nature of the conformational changes induced by each stage of the hydrolytic cycle of ATP and how they are coupled to protein translocation are not well understood. The str...
Autores principales: | Whitehouse, Sarah, Gold, Vicki A.M., Robson, Alice, Allen, William J., Sessions, Richard B., Collinson, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518217/ https://www.ncbi.nlm.nih.gov/pubmed/23209305 http://dx.doi.org/10.1083/jcb.201205191 |
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