Cargando…

Nanoparticle-conjugated animal venom-toxins and their possible therapeutic potential

Nano-medical approaches to develop drugs have attracted much attention in different arenas to design nanoparticle conjugates for better efficacy of the potential bio-molecules. A group of promising candidates of this category would be venom-toxins of animal origin of potential medicinal value. Tradi...

Descripción completa

Detalles Bibliográficos
Autores principales: Biswas, Archita, Gomes, Aparna, Sengupta, Jayeeta, Datta, Poulami, Singha, Santiswarup, Dasgupta, Anjan Kr, Gomes, Antony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Library Publishing Media 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518302/
https://www.ncbi.nlm.nih.gov/pubmed/23236583
_version_ 1782252554473701376
author Biswas, Archita
Gomes, Aparna
Sengupta, Jayeeta
Datta, Poulami
Singha, Santiswarup
Dasgupta, Anjan Kr
Gomes, Antony
author_facet Biswas, Archita
Gomes, Aparna
Sengupta, Jayeeta
Datta, Poulami
Singha, Santiswarup
Dasgupta, Anjan Kr
Gomes, Antony
author_sort Biswas, Archita
collection PubMed
description Nano-medical approaches to develop drugs have attracted much attention in different arenas to design nanoparticle conjugates for better efficacy of the potential bio-molecules. A group of promising candidates of this category would be venom-toxins of animal origin of potential medicinal value. Traditional systems of medicine as well as folklores mention the use of venom-toxins for the treatment of various diseases. Research has led to scientific validation of medicinal applications of venoms-toxins and many active constituents derived from venoms-toxins are already in clinical use or under clinical trial. Nanomedicine is an emerging field of medicine where nanotechnology is used to develop molecules of nano-scale dimension, so that these molecules can be taken up by the cells more easily and have better efficacy, as compared to large molecules that may tend to get eliminated. This review will focus on some of the potential venoms and toxins along with nanoparticle conjugated venom-toxins of snakes, amphibians, scorpions and bees, etc., for possible therapeutic clues against emerging diseases.
format Online
Article
Text
id pubmed-3518302
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Library Publishing Media
record_format MEDLINE/PubMed
spelling pubmed-35183022012-12-12 Nanoparticle-conjugated animal venom-toxins and their possible therapeutic potential Biswas, Archita Gomes, Aparna Sengupta, Jayeeta Datta, Poulami Singha, Santiswarup Dasgupta, Anjan Kr Gomes, Antony J Venom Res Review Article Nano-medical approaches to develop drugs have attracted much attention in different arenas to design nanoparticle conjugates for better efficacy of the potential bio-molecules. A group of promising candidates of this category would be venom-toxins of animal origin of potential medicinal value. Traditional systems of medicine as well as folklores mention the use of venom-toxins for the treatment of various diseases. Research has led to scientific validation of medicinal applications of venoms-toxins and many active constituents derived from venoms-toxins are already in clinical use or under clinical trial. Nanomedicine is an emerging field of medicine where nanotechnology is used to develop molecules of nano-scale dimension, so that these molecules can be taken up by the cells more easily and have better efficacy, as compared to large molecules that may tend to get eliminated. This review will focus on some of the potential venoms and toxins along with nanoparticle conjugated venom-toxins of snakes, amphibians, scorpions and bees, etc., for possible therapeutic clues against emerging diseases. Library Publishing Media 2012-10-23 /pmc/articles/PMC3518302/ /pubmed/23236583 Text en © Copyright The Author(s) http://creativecommons.org/licenses/by-nc/2.5 Published by Library Publishing Media. This is an open access article, published under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5). This license permits non-commercial use, distribution and reproduction of the article, provided the original work is appropriately acknowledged with correct citation details.
spellingShingle Review Article
Biswas, Archita
Gomes, Aparna
Sengupta, Jayeeta
Datta, Poulami
Singha, Santiswarup
Dasgupta, Anjan Kr
Gomes, Antony
Nanoparticle-conjugated animal venom-toxins and their possible therapeutic potential
title Nanoparticle-conjugated animal venom-toxins and their possible therapeutic potential
title_full Nanoparticle-conjugated animal venom-toxins and their possible therapeutic potential
title_fullStr Nanoparticle-conjugated animal venom-toxins and their possible therapeutic potential
title_full_unstemmed Nanoparticle-conjugated animal venom-toxins and their possible therapeutic potential
title_short Nanoparticle-conjugated animal venom-toxins and their possible therapeutic potential
title_sort nanoparticle-conjugated animal venom-toxins and their possible therapeutic potential
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518302/
https://www.ncbi.nlm.nih.gov/pubmed/23236583
work_keys_str_mv AT biswasarchita nanoparticleconjugatedanimalvenomtoxinsandtheirpossibletherapeuticpotential
AT gomesaparna nanoparticleconjugatedanimalvenomtoxinsandtheirpossibletherapeuticpotential
AT senguptajayeeta nanoparticleconjugatedanimalvenomtoxinsandtheirpossibletherapeuticpotential
AT dattapoulami nanoparticleconjugatedanimalvenomtoxinsandtheirpossibletherapeuticpotential
AT singhasantiswarup nanoparticleconjugatedanimalvenomtoxinsandtheirpossibletherapeuticpotential
AT dasguptaanjankr nanoparticleconjugatedanimalvenomtoxinsandtheirpossibletherapeuticpotential
AT gomesantony nanoparticleconjugatedanimalvenomtoxinsandtheirpossibletherapeuticpotential