Reversible switching between epigenetic states in honeybee behavioral subcastes

In honeybee societies, distinct caste phenotypes are created from the same genotype, suggesting a role for epigenetics in deriving these behaviorally different phenotypes. We found no differences in DNA methylation between irreversible worker/queen castes, but substantial differences between nurses...

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Autores principales: Herb, Brian R., Wolschin, Florian, Hansen, Kasper D., Aryee, Martin J., Langmead, Ben, Irizarry, Rafael, Amdam, Gro V., Feinberg, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518384/
https://www.ncbi.nlm.nih.gov/pubmed/22983211
http://dx.doi.org/10.1038/nn.3218
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author Herb, Brian R.
Wolschin, Florian
Hansen, Kasper D.
Aryee, Martin J.
Langmead, Ben
Irizarry, Rafael
Amdam, Gro V.
Feinberg, Andrew P.
author_facet Herb, Brian R.
Wolschin, Florian
Hansen, Kasper D.
Aryee, Martin J.
Langmead, Ben
Irizarry, Rafael
Amdam, Gro V.
Feinberg, Andrew P.
author_sort Herb, Brian R.
collection PubMed
description In honeybee societies, distinct caste phenotypes are created from the same genotype, suggesting a role for epigenetics in deriving these behaviorally different phenotypes. We found no differences in DNA methylation between irreversible worker/queen castes, but substantial differences between nurses and forager subcastes. Reverting foragers back to nurses reestablished methylation levels for a majority of genes and provided the first evidence in any organism of reversible epigenetic changes associated with behavior.
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spelling pubmed-35183842013-04-01 Reversible switching between epigenetic states in honeybee behavioral subcastes Herb, Brian R. Wolschin, Florian Hansen, Kasper D. Aryee, Martin J. Langmead, Ben Irizarry, Rafael Amdam, Gro V. Feinberg, Andrew P. Nat Neurosci Article In honeybee societies, distinct caste phenotypes are created from the same genotype, suggesting a role for epigenetics in deriving these behaviorally different phenotypes. We found no differences in DNA methylation between irreversible worker/queen castes, but substantial differences between nurses and forager subcastes. Reverting foragers back to nurses reestablished methylation levels for a majority of genes and provided the first evidence in any organism of reversible epigenetic changes associated with behavior. 2012-09-16 2012-10 /pmc/articles/PMC3518384/ /pubmed/22983211 http://dx.doi.org/10.1038/nn.3218 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Herb, Brian R.
Wolschin, Florian
Hansen, Kasper D.
Aryee, Martin J.
Langmead, Ben
Irizarry, Rafael
Amdam, Gro V.
Feinberg, Andrew P.
Reversible switching between epigenetic states in honeybee behavioral subcastes
title Reversible switching between epigenetic states in honeybee behavioral subcastes
title_full Reversible switching between epigenetic states in honeybee behavioral subcastes
title_fullStr Reversible switching between epigenetic states in honeybee behavioral subcastes
title_full_unstemmed Reversible switching between epigenetic states in honeybee behavioral subcastes
title_short Reversible switching between epigenetic states in honeybee behavioral subcastes
title_sort reversible switching between epigenetic states in honeybee behavioral subcastes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518384/
https://www.ncbi.nlm.nih.gov/pubmed/22983211
http://dx.doi.org/10.1038/nn.3218
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