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High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries
We introduce two large-scale resources for functional analysis of microRNA—a decoy/sponge library for inhibiting microRNA function and a sensor library for monitoring microRNA activity. To take advantage of the sensor library, we developed a high-throughput assay called Sensor-seq, which permits the...
Autores principales: | Mullokandov, Gavriel, Baccarini, Alessia, Ruzo, Albert, Jayaprakash, Anitha D., Tung, Navpreet, Israelow, Benjamin, Evans, Matthew J., Sachidanandam, Ravi, Brown, Brian D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518396/ https://www.ncbi.nlm.nih.gov/pubmed/22751203 http://dx.doi.org/10.1038/nmeth.2078 |
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