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Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced IL-6 secretion

Toll-like receptors (TLRs) are critical mediators of the immune response to pathogens. The influence of human TLR6 polymorphisms on susceptibility to infection is only partially understood. Most microbes contain lipopeptides recognized by TLR2/1 or TLR2/6 heterodimers. Our aim was to determine wheth...

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Detalles Bibliográficos
Autores principales:	Shehu Shey, Muki, Randhawa, April Kaur, Bowmaker, Mark, Smith, Elizabeth, Jens Scriba, Thomas, de Kock, Marwou, Mahomed, Hassan, Hussey, Gregory, Richard Hawn, Thomas, Albert Hanekom, Willem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518443/ https://www.ncbi.nlm.nih.gov/pubmed/20445564 http://dx.doi.org/10.1038/gene.2010.14

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