ATP8B1 Gene Expression Is Driven by a Housekeeping-Like Promoter Independent of Bile Acids and Farnesoid X Receptor

BACKGROUND: Mutations in ATP8B1 gene were identified as a cause of low γ-glutamyltranspeptidase cholestasis with variable phenotype, ranging from Progressive Familial Intrahepatic Cholestasis to Benign Recurrent Intrahepatic Cholestasis. However, only the coding region of ATP8B1 has been described....

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Detalles Bibliográficos
Autores principales: Cebecauerová, Dita, Strautnieks, Sandra S., Byrne, Jane A., Jirsa, Milan, Thompson, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518472/
https://www.ncbi.nlm.nih.gov/pubmed/23251605
http://dx.doi.org/10.1371/journal.pone.0051650

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