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Expression patterns of the immunomodulatory enzyme arginase 1 in blood, lymph nodes and tumor tissue of early-stage breast cancer patients

Arginase 1 (ARG1) is an important enzyme in amino acid metabolism that also exerts immunoregulatory function. High ARG1 expression, which is associated with cell cycle arrest and functional unresponsiveness in T cells, has been observed after trauma, infections and in cancer patients. We studied ARG...

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Detalles Bibliográficos
Autores principales:	de Boniface, Jana, Mao, Yumeng, Schmidt-Mende, Jan, Kiessling, Rolf, Poschke, Isabel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518503/ https://www.ncbi.nlm.nih.gov/pubmed/23243594 http://dx.doi.org/10.4161/onci.21678

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