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Targeting dendritic cells in situ for breast cancer immunotherapy
We have recently developed a protein vaccine against breast cancer in which HER2 is delivered to dendritic cells (DCs) in vivo through receptors expressed on their surface. Our results indicate that this is a promising approach to induce durable, broad and integrated immunity against breast cancer.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518515/ https://www.ncbi.nlm.nih.gov/pubmed/23243606 http://dx.doi.org/10.4161/onci.20982 |
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author | Wang, Bei |
author_facet | Wang, Bei |
author_sort | Wang, Bei |
collection | PubMed |
description | We have recently developed a protein vaccine against breast cancer in which HER2 is delivered to dendritic cells (DCs) in vivo through receptors expressed on their surface. Our results indicate that this is a promising approach to induce durable, broad and integrated immunity against breast cancer. |
format | Online Article Text |
id | pubmed-3518515 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Landes Bioscience |
record_format | MEDLINE/PubMed |
spelling | pubmed-35185152012-12-14 Targeting dendritic cells in situ for breast cancer immunotherapy Wang, Bei Oncoimmunology Author's View We have recently developed a protein vaccine against breast cancer in which HER2 is delivered to dendritic cells (DCs) in vivo through receptors expressed on their surface. Our results indicate that this is a promising approach to induce durable, broad and integrated immunity against breast cancer. Landes Bioscience 2012-11-01 /pmc/articles/PMC3518515/ /pubmed/23243606 http://dx.doi.org/10.4161/onci.20982 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Author's View Wang, Bei Targeting dendritic cells in situ for breast cancer immunotherapy |
title | Targeting dendritic cells in situ for breast cancer immunotherapy |
title_full | Targeting dendritic cells in situ for breast cancer immunotherapy |
title_fullStr | Targeting dendritic cells in situ for breast cancer immunotherapy |
title_full_unstemmed | Targeting dendritic cells in situ for breast cancer immunotherapy |
title_short | Targeting dendritic cells in situ for breast cancer immunotherapy |
title_sort | targeting dendritic cells in situ for breast cancer immunotherapy |
topic | Author's View |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518515/ https://www.ncbi.nlm.nih.gov/pubmed/23243606 http://dx.doi.org/10.4161/onci.20982 |
work_keys_str_mv | AT wangbei targetingdendriticcellsinsituforbreastcancerimmunotherapy |