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Targeting dendritic cells in situ for breast cancer immunotherapy

We have recently developed a protein vaccine against breast cancer in which HER2 is delivered to dendritic cells (DCs) in vivo through receptors expressed on their surface. Our results indicate that this is a promising approach to induce durable, broad and integrated immunity against breast cancer.

Detalles Bibliográficos
Autor principal: Wang, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518515/
https://www.ncbi.nlm.nih.gov/pubmed/23243606
http://dx.doi.org/10.4161/onci.20982
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author Wang, Bei
author_facet Wang, Bei
author_sort Wang, Bei
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description We have recently developed a protein vaccine against breast cancer in which HER2 is delivered to dendritic cells (DCs) in vivo through receptors expressed on their surface. Our results indicate that this is a promising approach to induce durable, broad and integrated immunity against breast cancer.
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spelling pubmed-35185152012-12-14 Targeting dendritic cells in situ for breast cancer immunotherapy Wang, Bei Oncoimmunology Author's View We have recently developed a protein vaccine against breast cancer in which HER2 is delivered to dendritic cells (DCs) in vivo through receptors expressed on their surface. Our results indicate that this is a promising approach to induce durable, broad and integrated immunity against breast cancer. Landes Bioscience 2012-11-01 /pmc/articles/PMC3518515/ /pubmed/23243606 http://dx.doi.org/10.4161/onci.20982 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Wang, Bei
Targeting dendritic cells in situ for breast cancer immunotherapy
title Targeting dendritic cells in situ for breast cancer immunotherapy
title_full Targeting dendritic cells in situ for breast cancer immunotherapy
title_fullStr Targeting dendritic cells in situ for breast cancer immunotherapy
title_full_unstemmed Targeting dendritic cells in situ for breast cancer immunotherapy
title_short Targeting dendritic cells in situ for breast cancer immunotherapy
title_sort targeting dendritic cells in situ for breast cancer immunotherapy
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518515/
https://www.ncbi.nlm.nih.gov/pubmed/23243606
http://dx.doi.org/10.4161/onci.20982
work_keys_str_mv AT wangbei targetingdendriticcellsinsituforbreastcancerimmunotherapy