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Targeting cancer stem cells via dendritic-cell vaccination

Using syngeneic murine tumor models established in immunocompetent hosts, we showed that cancer stem cells are immunogenic and can be selectively targeted by dendritic cell-based vaccines. This new approach induced both humoral and cellular immune responses and conferred significantly superior antit...

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Detalles Bibliográficos
Autores principales: Teitz-Tennenbaum, Seagal, Wicha, Max S., Chang, Alfred E., Li, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518516/
https://www.ncbi.nlm.nih.gov/pubmed/23243607
http://dx.doi.org/10.4161/onci.21026