Parvoviruses-tools to fine-tune anticancer immune responses

Oncolytic virotherapy represents a recent approach to anticancer therapy. Rodent autonomous parvoviruses (PVs) represent naturally oncolytic viruses that are non-pathogenic for humans but possess and extended tropism, being capable of infecting transformed cells of both rodent and human origin. Rece...

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Detalles Bibliográficos
Autores principales: Grekova, Svitlana P., Rommelaere, Jean, Raykov, Zahari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518522/
https://www.ncbi.nlm.nih.gov/pubmed/23243613
http://dx.doi.org/10.4161/onci.21097
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author Grekova, Svitlana P.
Rommelaere, Jean
Raykov, Zahari
author_facet Grekova, Svitlana P.
Rommelaere, Jean
Raykov, Zahari
author_sort Grekova, Svitlana P.
collection PubMed
description Oncolytic virotherapy represents a recent approach to anticancer therapy. Rodent autonomous parvoviruses (PVs) represent naturally oncolytic viruses that are non-pathogenic for humans but possess and extended tropism, being capable of infecting transformed cells of both rodent and human origin. Recent work from our group demonstrate that PVs can act as direct lytic agents and adjuvants, stimulating antitumor immune responses against glioma and pancreatic ductal adenocarcinoma (PDAC).
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spelling pubmed-35185222012-12-14 Parvoviruses-tools to fine-tune anticancer immune responses Grekova, Svitlana P. Rommelaere, Jean Raykov, Zahari Oncoimmunology Author's View Oncolytic virotherapy represents a recent approach to anticancer therapy. Rodent autonomous parvoviruses (PVs) represent naturally oncolytic viruses that are non-pathogenic for humans but possess and extended tropism, being capable of infecting transformed cells of both rodent and human origin. Recent work from our group demonstrate that PVs can act as direct lytic agents and adjuvants, stimulating antitumor immune responses against glioma and pancreatic ductal adenocarcinoma (PDAC). Landes Bioscience 2012-11-01 /pmc/articles/PMC3518522/ /pubmed/23243613 http://dx.doi.org/10.4161/onci.21097 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Grekova, Svitlana P.
Rommelaere, Jean
Raykov, Zahari
Parvoviruses-tools to fine-tune anticancer immune responses
title Parvoviruses-tools to fine-tune anticancer immune responses
title_full Parvoviruses-tools to fine-tune anticancer immune responses
title_fullStr Parvoviruses-tools to fine-tune anticancer immune responses
title_full_unstemmed Parvoviruses-tools to fine-tune anticancer immune responses
title_short Parvoviruses-tools to fine-tune anticancer immune responses
title_sort parvoviruses-tools to fine-tune anticancer immune responses
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518522/
https://www.ncbi.nlm.nih.gov/pubmed/23243613
http://dx.doi.org/10.4161/onci.21097
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