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Two-photon optogenetics of dendritic spines and neural circuits in 3D
We demonstrate a two-photon optogenetic method that generates action potentials in neurons with single-cell precision, using the red-shifted opsin C1V1(T). We apply the method to optically map synaptic circuits in mouse neocortical brain slices and to activate small dendritic regions and individual...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518588/ https://www.ncbi.nlm.nih.gov/pubmed/23142873 http://dx.doi.org/10.1038/nmeth.2249 |