β-1,3-Glucan, Which Can Be Targeted by Drugs, Forms a Trabecular Scaffold in the Oocyst Walls of Toxoplasma and Eimeria

The walls of infectious pathogens, which are essential for transmission, pathogenesis, and diagnosis, contain sugar polymers that are defining structural features, e.g., β-1,3-glucan and chitin in fungi, chitin in Entamoeba cysts, β-1,3-GalNAc in Giardia cysts, and peptidoglycans in bacteria. The go...

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Detalles Bibliográficos
Autores principales: Bushkin, G. Guy, Motari, Edwin, Magnelli, Paula, Gubbels, Marc-Jan, Dubey, Jitender P., Miska, Katarzyna B., Bullitt, Esther, Costello, Catherine E., Robbins, Phillips W., Samuelson, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518913/
https://www.ncbi.nlm.nih.gov/pubmed/23015739
http://dx.doi.org/10.1128/mBio.00258-12

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