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Kartagener's syndrome: A case series
Kartagener's syndrome is a rare, autosomal recessive genetic ciliary disorder comprising the triad of situs inversus, chronic sinusitis, and bronchiectasis. The basic problem lies in the defective movement of cilia, leading to recurrent chest infections, ear/nose/throat symptoms, and infertilit...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519024/ https://www.ncbi.nlm.nih.gov/pubmed/23243352 http://dx.doi.org/10.4103/0970-2113.102831 |
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author | Mishra, Mayank Kumar, Naresh Jaiswal, Ashish Verma, Ajay K. Kant, Surya |
author_facet | Mishra, Mayank Kumar, Naresh Jaiswal, Ashish Verma, Ajay K. Kant, Surya |
author_sort | Mishra, Mayank |
collection | PubMed |
description | Kartagener's syndrome is a rare, autosomal recessive genetic ciliary disorder comprising the triad of situs inversus, chronic sinusitis, and bronchiectasis. The basic problem lies in the defective movement of cilia, leading to recurrent chest infections, ear/nose/throat symptoms, and infertility. We hereby report three unusual cases of this rare entity – an infertile male with azoospermia in whom Bochdalek's diaphragmatic hernia coexisted, another case of an infertile female, and a third of an infertile male with oligospermia. The need for a high index of suspicion to make an early diagnosis cannot be overemphasized in such patients so that wherever possible, options for timely treatment of infertility may be offered and unnecessary evaluation of symptoms is avoided. |
format | Online Article Text |
id | pubmed-3519024 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-35190242012-12-14 Kartagener's syndrome: A case series Mishra, Mayank Kumar, Naresh Jaiswal, Ashish Verma, Ajay K. Kant, Surya Lung India Case Report Kartagener's syndrome is a rare, autosomal recessive genetic ciliary disorder comprising the triad of situs inversus, chronic sinusitis, and bronchiectasis. The basic problem lies in the defective movement of cilia, leading to recurrent chest infections, ear/nose/throat symptoms, and infertility. We hereby report three unusual cases of this rare entity – an infertile male with azoospermia in whom Bochdalek's diaphragmatic hernia coexisted, another case of an infertile female, and a third of an infertile male with oligospermia. The need for a high index of suspicion to make an early diagnosis cannot be overemphasized in such patients so that wherever possible, options for timely treatment of infertility may be offered and unnecessary evaluation of symptoms is avoided. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3519024/ /pubmed/23243352 http://dx.doi.org/10.4103/0970-2113.102831 Text en Copyright: © Lung India http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Mishra, Mayank Kumar, Naresh Jaiswal, Ashish Verma, Ajay K. Kant, Surya Kartagener's syndrome: A case series |
title | Kartagener's syndrome: A case series |
title_full | Kartagener's syndrome: A case series |
title_fullStr | Kartagener's syndrome: A case series |
title_full_unstemmed | Kartagener's syndrome: A case series |
title_short | Kartagener's syndrome: A case series |
title_sort | kartagener's syndrome: a case series |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519024/ https://www.ncbi.nlm.nih.gov/pubmed/23243352 http://dx.doi.org/10.4103/0970-2113.102831 |
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