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Atypical clinical course subacute sclerosing panencephalitis presenting as acute Encephalitis

We report a 14-year-old boy who presented with loss of consciousness and gait instability. The electroencephalogram (EEG) showed generalized slowing with irregular activity and cerebral magnetic imaging revealed asymmetrical nonspecific signals on basal ganglia. His second electroencephalogram revea...

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Autores principales: Komur, Mustafa, Arslankoylu, Ali E, Okuyaz, Cetin, Kuyucu, Necdet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519069/
https://www.ncbi.nlm.nih.gov/pubmed/23248691
http://dx.doi.org/10.4103/1817-1745.102574
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author Komur, Mustafa
Arslankoylu, Ali E
Okuyaz, Cetin
Kuyucu, Necdet
author_facet Komur, Mustafa
Arslankoylu, Ali E
Okuyaz, Cetin
Kuyucu, Necdet
author_sort Komur, Mustafa
collection PubMed
description We report a 14-year-old boy who presented with loss of consciousness and gait instability. The electroencephalogram (EEG) showed generalized slowing with irregular activity and cerebral magnetic imaging revealed asymmetrical nonspecific signals on basal ganglia. His second electroencephalogram revealed periodical generalized high-voltage slow wave complexes which did not disappear with diazepam induction. Subacute sclerosing panencephalitis (SSPE) was considered and the diagnosis was confirmed with the identification of measles antibodies in cerebrospinal fluid. Our findings show that SSPE should be in mind in the differential diagnosis of meningoencephalitis and acute disseminated encephalomyelitis and highlight the significance of EEG in the diagnosis of unidentified cases.
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spelling pubmed-35190692012-12-17 Atypical clinical course subacute sclerosing panencephalitis presenting as acute Encephalitis Komur, Mustafa Arslankoylu, Ali E Okuyaz, Cetin Kuyucu, Necdet J Pediatr Neurosci Case Report We report a 14-year-old boy who presented with loss of consciousness and gait instability. The electroencephalogram (EEG) showed generalized slowing with irregular activity and cerebral magnetic imaging revealed asymmetrical nonspecific signals on basal ganglia. His second electroencephalogram revealed periodical generalized high-voltage slow wave complexes which did not disappear with diazepam induction. Subacute sclerosing panencephalitis (SSPE) was considered and the diagnosis was confirmed with the identification of measles antibodies in cerebrospinal fluid. Our findings show that SSPE should be in mind in the differential diagnosis of meningoencephalitis and acute disseminated encephalomyelitis and highlight the significance of EEG in the diagnosis of unidentified cases. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3519069/ /pubmed/23248691 http://dx.doi.org/10.4103/1817-1745.102574 Text en Copyright: © Journal of Pediatric Neurosciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Komur, Mustafa
Arslankoylu, Ali E
Okuyaz, Cetin
Kuyucu, Necdet
Atypical clinical course subacute sclerosing panencephalitis presenting as acute Encephalitis
title Atypical clinical course subacute sclerosing panencephalitis presenting as acute Encephalitis
title_full Atypical clinical course subacute sclerosing panencephalitis presenting as acute Encephalitis
title_fullStr Atypical clinical course subacute sclerosing panencephalitis presenting as acute Encephalitis
title_full_unstemmed Atypical clinical course subacute sclerosing panencephalitis presenting as acute Encephalitis
title_short Atypical clinical course subacute sclerosing panencephalitis presenting as acute Encephalitis
title_sort atypical clinical course subacute sclerosing panencephalitis presenting as acute encephalitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519069/
https://www.ncbi.nlm.nih.gov/pubmed/23248691
http://dx.doi.org/10.4103/1817-1745.102574
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