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Boesenbergia rotunda: From Ethnomedicine to Drug Discovery
Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae family. B. rotunda is widely found in Asian countries where it is commonly used as a food ingredient and in ethnomedicinal preparations. The popularity of its ethnomedicinal usage has drawn the attention of scientist...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519102/ https://www.ncbi.nlm.nih.gov/pubmed/23243448 http://dx.doi.org/10.1155/2012/473637 |
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author | Eng-Chong, Tan Yean-Kee, Lee Chin-Fei, Chee Choon-Han, Heh Sher-Ming, Wong Li-Ping, Christina Thio Gen-Teck, Foo Khalid, Norzulaani Abd Rahman, Noorsaadah Karsani, Saiful Anuar Othman, Shatrah Othman, Rozana Yusof, Rohana |
author_facet | Eng-Chong, Tan Yean-Kee, Lee Chin-Fei, Chee Choon-Han, Heh Sher-Ming, Wong Li-Ping, Christina Thio Gen-Teck, Foo Khalid, Norzulaani Abd Rahman, Noorsaadah Karsani, Saiful Anuar Othman, Shatrah Othman, Rozana Yusof, Rohana |
author_sort | Eng-Chong, Tan |
collection | PubMed |
description | Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae family. B. rotunda is widely found in Asian countries where it is commonly used as a food ingredient and in ethnomedicinal preparations. The popularity of its ethnomedicinal usage has drawn the attention of scientists worldwide to further investigate its medicinal properties. Advancement in drug design and discovery research has led to the development of synthetic drugs from B. rotunda metabolites via bioinformatics and medicinal chemistry studies. Furthermore, with the advent of genomics, transcriptomics, proteomics, and metabolomics, new insights on the biosynthetic pathways of B. rotunda metabolites can be elucidated, enabling researchers to predict the potential bioactive compounds responsible for the medicinal properties of the plant. The vast biological activities exhibited by the compounds obtained from B. rotunda warrant further investigation through studies such as drug discovery, polypharmacology, and drug delivery using nanotechnology. |
format | Online Article Text |
id | pubmed-3519102 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-35191022012-12-14 Boesenbergia rotunda: From Ethnomedicine to Drug Discovery Eng-Chong, Tan Yean-Kee, Lee Chin-Fei, Chee Choon-Han, Heh Sher-Ming, Wong Li-Ping, Christina Thio Gen-Teck, Foo Khalid, Norzulaani Abd Rahman, Noorsaadah Karsani, Saiful Anuar Othman, Shatrah Othman, Rozana Yusof, Rohana Evid Based Complement Alternat Med Review Article Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae family. B. rotunda is widely found in Asian countries where it is commonly used as a food ingredient and in ethnomedicinal preparations. The popularity of its ethnomedicinal usage has drawn the attention of scientists worldwide to further investigate its medicinal properties. Advancement in drug design and discovery research has led to the development of synthetic drugs from B. rotunda metabolites via bioinformatics and medicinal chemistry studies. Furthermore, with the advent of genomics, transcriptomics, proteomics, and metabolomics, new insights on the biosynthetic pathways of B. rotunda metabolites can be elucidated, enabling researchers to predict the potential bioactive compounds responsible for the medicinal properties of the plant. The vast biological activities exhibited by the compounds obtained from B. rotunda warrant further investigation through studies such as drug discovery, polypharmacology, and drug delivery using nanotechnology. Hindawi Publishing Corporation 2012 2012-11-27 /pmc/articles/PMC3519102/ /pubmed/23243448 http://dx.doi.org/10.1155/2012/473637 Text en Copyright © 2012 Tan Eng-Chong et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Eng-Chong, Tan Yean-Kee, Lee Chin-Fei, Chee Choon-Han, Heh Sher-Ming, Wong Li-Ping, Christina Thio Gen-Teck, Foo Khalid, Norzulaani Abd Rahman, Noorsaadah Karsani, Saiful Anuar Othman, Shatrah Othman, Rozana Yusof, Rohana Boesenbergia rotunda: From Ethnomedicine to Drug Discovery |
title |
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery |
title_full |
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery |
title_fullStr |
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery |
title_full_unstemmed |
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery |
title_short |
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery |
title_sort | boesenbergia rotunda: from ethnomedicine to drug discovery |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519102/ https://www.ncbi.nlm.nih.gov/pubmed/23243448 http://dx.doi.org/10.1155/2012/473637 |
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