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ADAM17 Silencing in Mouse Colon Carcinoma Cells: The Effect on Tumoricidal Cytokines and Angiogenesis

ADAM17 (a disintegrin and metalloprotease 17) is a major sheddase for numerous growth factors, cytokines, receptors, and cell adhesion molecules and is often overexpressed in malignant cells. It is generally accepted that ADAM17 promotes tumor development via activating growth factors from the EGF f...

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Detalles Bibliográficos
Autores principales: Das, Sudipta, Czarnek, Maria, Bzowska, Monika, Mężyk-Kopeć, Renata, Stalińska, Krystyna, Wyroba, Barbara, Sroka, Jolanta, Jucha, Jarosław, Deneka, Dawid, Stokłosa, Paulina, Ogonek, Justyna, Swartz, Melody A., Madeja, Zbigniew, Bereta, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519469/
https://www.ncbi.nlm.nih.gov/pubmed/23251384
http://dx.doi.org/10.1371/journal.pone.0050791