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CCl(4)-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat

BACKGROUND: Rutin is a polyphenolic natural flavonoid which possesses antioxidant and anticancer activity. In the present study the hepatoprotective effect of rutin was evaluated against carbon tetrachloride (CCl(4))-induced liver injuries in rats. METHODS AND MATERIALS: 24 Sprague–Dawley male rats...

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Detalles Bibliográficos
Autores principales: Khan, Rahmat A, Khan, Muhammad R, Sahreen, Sumaira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519517/
https://www.ncbi.nlm.nih.gov/pubmed/23043521
http://dx.doi.org/10.1186/1472-6882-12-178