Genome-Wide Analysis of DNA Methylation Differences in Muscle and Fat from Monozygotic Twins Discordant for Type 2 Diabetes

BACKGROUND: Monozygotic twins discordant for type 2 diabetes constitute an ideal model to study environmental contributions to type 2 diabetic traits. We aimed to examine whether global DNA methylation differences exist in major glucose metabolic tissues from these twins. METHODOLOGY/PRINCIPAL FINDI...

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Detalles Bibliográficos
Autores principales: Ribel-Madsen, Rasmus, Fraga, Mario F., Jacobsen, Stine, Bork-Jensen, Jette, Lara, Ester, Calvanese, Vincenzo, Fernandez, Agustin F., Friedrichsen, Martin, Vind, Birgitte F., Højlund, Kurt, Beck-Nielsen, Henning, Esteller, Manel, Vaag, Allan, Poulsen, Pernille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519577/
https://www.ncbi.nlm.nih.gov/pubmed/23251491
http://dx.doi.org/10.1371/journal.pone.0051302

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