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Blood leukocytes from benznidazole-treated indeterminate chagas disease patients display an overall type-1-modulated cytokine profile upon short-term in vitro stimulation with trypanosoma cruzi antigens
BACKGROUND: Benznidazole (Bz)-chemotherapy is recommended to prevent Chagas disease progression, despite its limited efficacy during chronic disease. However, the host mechanisms underlying these benefits still remain to be elucidated. METHODS: In this study, we have used short-term whole blood cult...
Autores principales: | Sathler-Avelar, Renato, Vitelli-Avelar, Danielle Marquete, Elói-Santos, Silvana Maria, Gontijo, Eliane Dias, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519593/ https://www.ncbi.nlm.nih.gov/pubmed/22625224 http://dx.doi.org/10.1186/1471-2334-12-123 |
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