Deletion of TAK1 in the Myeloid Lineage Results in the Spontaneous Development of Myelomonocytic Leukemia in Mice

Previous studies of the conditional ablation of TGF-β activated kinase 1 (TAK1) in mice indicate that TAK1 has an obligatory role in the survival and/or development of hematopoietic stem cells, B cells, T cells, hepatocytes, intestinal epithelial cells, keratinocytes, and various tissues, primarily...

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Detalles Bibliográficos
Autores principales: Lamothe, Betty, Lai, YunJu, Hur, Lana, Orozco, Natalia Martin, Wang, Jing, Campos, Alejandro D., Xie, Min, Schneider, Michael D., Lockworth, Cynthia R., Jakacky, Jared, Tran, Diep, Ho, Michael, Dawud, Sity, Dong, Chen, Lin, Hui-Kuan, Hu, Peter, Estrov, Zeev, Bueso-Ramos, Carlos E., Darnay, Bryant G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519594/
https://www.ncbi.nlm.nih.gov/pubmed/23251462
http://dx.doi.org/10.1371/journal.pone.0051228

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