Deletion of the TNFAIP3/A20 gene detected by FICTION analysis in classical Hodgkin lymphoma

BACKGROUND: The TNFAIP3 gene, which encodes a ubiquitin-modifying enzyme (A20) involved in the negative regulation of NF-κB signaling, is frequently inactivated by gene deletions/mutations in a variety of B-cell malignancies. However, the detection of this in primary Hodgkin lymphoma (HL) specimens...

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Detalles Bibliográficos
Autores principales: Nomoto, Junko, Hiramoto, Nobuhiro, Kato, Motohiro, Sanada, Masashi, Maeshima, Akiko Miyagi, Taniguchi, Hirokazu, Hosoda, Fumie, Asakura, Yoshitaka, Munakata, Wataru, Sekiguchi, Naohiro, Maruyama, Dai, Watanabe, Takashi, Nakagama, Hitoshi, Takeuchi, Kengo, Tobinai, Kensei, Ogawa, Seishi, Kobayashi, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519598/
https://www.ncbi.nlm.nih.gov/pubmed/23039325
http://dx.doi.org/10.1186/1471-2407-12-457

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