The oncoprotein and stem cell renewal factor BMI1 associates with poor clinical outcome in oesophageal cancer patients undergoing preoperative chemoradiotherapy

BACKGROUND: The polycomb group (PcG) family BMI1, acting downstream of the hedgehog (Hh) pathway, plays an essential role in the self-renewal of haematopoietic, neural, and intestinal stem cells, and is dysregulated in many types of cancer. Our recent report has demonstrated that Hh signalling activ...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshikawa, Reigetsu, Tsujimura, Tohru, Tao, Lihua, Kamikonya, Norihiko, Fujiwara, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519675/
https://www.ncbi.nlm.nih.gov/pubmed/23046527
http://dx.doi.org/10.1186/1471-2407-12-461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519675/
https://www.ncbi.nlm.nih.gov/pubmed/23046527
http://dx.doi.org/10.1186/1471-2407-12-461

Ejemplares similares