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The ChIP-seq-Defined Networks of Bcl-3 Gene Binding Support Its Required Role in Skeletal Muscle Atrophy

NF-kappaB transcriptional activation is required for skeletal muscle disuse atrophy. We are continuing to study how the activation of NF-kB regulates the genes that encode the protein products that cause atrophy. Using ChIP-sequencing we found that Bcl-3, an NF-kB transcriptional activator required...

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Detalles Bibliográficos
Autores principales: Jackman, Robert W., Wu, Chia-Ling, Kandarian, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519692/
https://www.ncbi.nlm.nih.gov/pubmed/23251550
http://dx.doi.org/10.1371/journal.pone.0051478

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