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High DNA Methyltransferase DNMT3B Levels: A Poor Prognostic Marker in Acute Myeloid Leukemia

It has been recently shown that DNA methyl transferase overexpression is correlated with unfavourable prognosis in human malignancies while methylation deregulation remains a hallmark that defines acute myeloid leukemia (AML). The oncogenic transcription factor EVI1 is involved in methylation deregu...

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Detalles Bibliográficos
Autores principales:	Hayette, Sandrine, Thomas, Xavier, Jallades, Laurent, Chabane, Kaddour, Charlot, Carole, Tigaud, Isabelle, Gazzo, Sophie, Morisset, Stéphane, Cornillet-Lefebvre, Pascale, Plesa, Adriana, Huet, Sarah, Renneville, Aline, Salles, Gilles, Nicolini, Franck Emmanuel, Magaud, Jean-Pierre, Michallet, Mauricette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519733/ https://www.ncbi.nlm.nih.gov/pubmed/23251566 http://dx.doi.org/10.1371/journal.pone.0051527

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