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The role of TLR2 in the host response to pneumococcal pneumonia in absence of the spleen

BACKGROUND: Asplenic individuals are susceptible for overwhelming infection with Streptococcus pneumoniae, carrying a high mortality. Although Toll-like receptor (TLR)-2 is considered the major receptor for Gram-positive bacteria in innate immunity, it does not play a major role in host defense agai...

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Detalles Bibliográficos
Autores principales:	Lammers, Adriana J J, de Porto, AlexanderPNA, de Boer, Onno J, Florquin, Sandrine, van der Poll, Tom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519748/ https://www.ncbi.nlm.nih.gov/pubmed/22721450 http://dx.doi.org/10.1186/1471-2334-12-139

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