Cargando…

Genetically Encoded Green Fluorescent Ca(2+) Indicators with Improved Detectability for Neuronal Ca(2+) Signals

Imaging the activities of individual neurons with genetically encoded Ca(2+) indicators (GECIs) is a promising method for understanding neuronal network functions. Here, we report GECIs with improved neuronal Ca(2+) signal detectability, termed G-CaMP6 and G-CaMP8. Compared to a series of existing G...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ohkura, Masamichi, Sasaki, Takuya, Sadakari, Junko, Gengyo-Ando, Keiko, Kagawa-Nagamura, Yuko, Kobayashi, Chiaki, Ikegaya, Yuji, Nakai, Junichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519846/ https://www.ncbi.nlm.nih.gov/pubmed/23240011 http://dx.doi.org/10.1371/journal.pone.0051286

Ejemplares similares

An Improved Genetically Encoded Red Fluorescent Ca(2+) Indicator for Detecting Optically Evoked Action Potentials
por: Ohkura, Masamichi, et al.
Publicado: (2012)

Role of tyramine in calcium dynamics of GABAergic neurons and escape behavior in Caenorhabditis elegans
por: Kagawa-Nagamura, Yuko, et al.
Publicado: (2018)

Generation and Imaging of Transgenic Mice that Express G-CaMP7 under a Tetracycline Response Element
por: Sato, Masaaki, et al.
Publicado: (2015)

Cellular identity and Ca(2+) signaling activity of the non-reproductive GnRH system in the Ciona intestinalis type A (Ciona robusta) larva
por: Okawa, Nanako, et al.
Publicado: (2020)

Imaging intraorganellar Ca(2+) at subcellular resolution using CEPIA
por: Suzuki, Junji, et al.
Publicado: (2014)

Juvenile Hippocampal CA2 Region Expresses Aggrecan
por: Noguchi, Asako, et al.
Publicado: (2017)

Nanodomain Ca(2+) of Ca(2+) channels detected by a tethered genetically encoded Ca(2+) sensor
por: Tay, Lai Hock, et al.
Publicado: (2012)

Astrocytic Ca(2+) signals are required for the functional integrity of tripartite synapses
por: Tanaka, Mika, et al.
Publicado: (2013)

Machine learning-based segmentation of the rodent hippocampal CA2 area from Nissl-stained sections
por: Takeuchi, Yuki, et al.
Publicado: (2023)

An R-CaMP1.07 reporter mouse for cell-type-specific expression of a sensitive red fluorescent calcium indicator
por: Bethge, Philipp, et al.
Publicado: (2017)

A Statistical Method of Identifying Interactions in Neuron–Glia Systems Based on Functional Multicell Ca2+ Imaging
por: Nakae, Ken, et al.
Publicado: (2014)

K(+) and Ca(2+) Channels Regulate Ca(2+) Signaling in Chondrocytes: An Illustrated Review
por: Suzuki, Yoshiaki, et al.
Publicado: (2020)

Specific AAV2/PHP.eB-mediated gene transduction of CA2 pyramidal cells via injection into the lateral ventricle
por: Okamoto, Kazuki, et al.
Publicado: (2023)

Divergence of Ca(2+) selectivity and equilibrium Ca(2+) blockade in a Ca(2+) release-activated Ca(2+) channel
por: Yamashita, Megumi, et al.
Publicado: (2014)

Highlighted Ca(2+) imaging with a genetically encoded ‘caged’ indicator
por: Matsuda, Tomoki, et al.
Publicado: (2013)

Routes of Ca(2+) Shuttling during Ca(2+) Oscillations: FOCUS ON THE ROLE OF MITOCHONDRIAL Ca(2+) HANDLING AND CYTOSOLIC Ca(2+) BUFFERS
por: Pecze, László, et al.
Publicado: (2015)

Cytosolic Ca(2+)-dependent Ca(2+) release activity primarily determines the ER Ca(2+) level in cells expressing the CPVT-linked mutant RYR2
por: Kurebayashi, Nagomi, et al.
Publicado: (2022)

Two-photon calcium imaging of the medial prefrontal cortex and hippocampus without cortical invasion
por: Kondo, Masashi, et al.
Publicado: (2017)

Multiple coordinated cellular dynamics mediate CA1 map plasticity
por: Mizuta, Kotaro, et al.
Publicado: (2021)

Synthesis of Al(2)Ca Dispersoids by Powder Metallurgy Using a Mg–Al Alloy and CaO Particles
por: Fujita, Junji, et al.
Publicado: (2017)

Ca(2+)-Induced Ca(2+) Release through Localized Ca(2+) Uncaging in Smooth Muscle
por: Ji, Guangju, et al.
Publicado: (2006)

Effects of a high-sodium diet on renal tubule Ca(2+) transporter and claudin expression in Wistar-Kyoto rats
por: Yatabe, Midori Sasaki, et al.
Publicado: (2012)

Generation and characterization of a lysosomally targeted, genetically encoded Ca(2+)-sensor
por: McCue, Hannah V., et al.
Publicado: (2012)

Localized Ca(2+) uncaging reveals polarized distribution of Ca(2+)-sensitive Ca(2+) release sites: mechanism of unidirectional Ca(2+) waves
por: Ashby, Michael C., et al.
Publicado: (2002)

Cannabinoids disrupt memory encoding by functionally isolating hippocampal CA1 from CA3
por: Sandler, Roman A., et al.
Publicado: (2017)

Distinct place cell dynamics in CA1 and CA3 encode experience in new environments
por: Dong, Can, et al.
Publicado: (2021)

The effects of Ca(2+) buffers on cytosolic Ca(2+) signalling
por: Petersen, Ole H.
Publicado: (2017)

Prostaglandin D(2) Induces Ca(2+) Sensitization of Contraction without Affecting Cytosolic Ca(2+) Level in Bronchial Smooth Muscle
por: Suto, Wataru, et al.
Publicado: (2018)

Presenilin-2 dampens intracellular Ca(2+) stores by increasing Ca(2+) leakage and reducing Ca(2+) uptake
por: Brunello, Lucia, et al.
Publicado: (2009)

Regulation of the cardiac Na(+)-Ca2+ exchanger by Ca2+. Mutational analysis of the Ca(2+)-binding domain
Publicado: (1995)

Ca(2+) influx and the store-operated Ca(2+) entry pathway undergo regulation during mouse oocyte maturation
por: Cheon, Banyoon, et al.
Publicado: (2013)

Super-wide-field two-photon imaging with a micro-optical device moving in post-objective space
por: Terada, Shin-Ichiro, et al.
Publicado: (2018)

Aspirin Induces Mitochondrial Ca(2+) Remodeling in Tumor Cells via ROS‒Depolarization‒Voltage-Gated Ca(2+) Entry
por: Fujikawa, Itsuho, et al.
Publicado: (2020)

Amino Acid-Mediated Intracellular Ca(2+) Rise Modulates mTORC1 by Regulating the TSC2-Rheb Axis through Ca(2+)/Calmodulin
por: Amemiya, Yuna, et al.
Publicado: (2021)

Mapping the BK(Ca) Channel's “Ca(2+) Bowl”: Side-chains Essential for Ca(2+) Sensing
por: Bao, Lin, et al.
Publicado: (2004)

Comparison of the Sulfonamide Inhibition Profiles of the α-Carbonic Anhydrase Isoforms (SpiCA1, SpiCA2 and SpiCA3) Encoded by the Genome of the Scleractinian Coral Stylophora pistillata
por: Del Prete, Sonia, et al.
Publicado: (2019)

Molecular moieties masking Ca(2+)-dependent facilitation of voltage-gated Ca(v)2.2 Ca(2+) channels
por: Thomas, Jessica R., et al.
Publicado: (2018)

Does CaMKII decode Ca(2+) oscillations?
por: Pinto, Thiago M, et al.
Publicado: (2012)

Total Matrix Ca(2+) Modulates Ca(2+) Efflux via the Ca(2+)/H(+) Exchanger in Cardiac Mitochondria
por: Natarajan, Gayathri K., et al.
Publicado: (2020)

Editorial: Ca(2+) signalling in plant biotic interactions
por: DeFalco, Thomas A., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1aguarkvdj1qkikcid3p445dli