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Pregnenolone Rescues Schizophrenia-Like Behavior in Dopamine Transporter Knockout Mice

Pregnenolone belongs to a class of endogenous neurosteroids in the central nervous system (CNS), which has been suggested to enhance cognitive functions through GABA(A) receptor signaling by its metabolites. It has been shown that the level of pregnenolone is altered in certain brain areas of schizo...

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Detalles Bibliográficos
Autores principales: Wong, Peiyan, Chang, Cecilia Chin Roei, Marx, Christine E., Caron, Marc G., Wetsel, William C., Zhang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519851/
https://www.ncbi.nlm.nih.gov/pubmed/23240026
http://dx.doi.org/10.1371/journal.pone.0051455

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