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Pregnenolone Rescues Schizophrenia-Like Behavior in Dopamine Transporter Knockout Mice
Pregnenolone belongs to a class of endogenous neurosteroids in the central nervous system (CNS), which has been suggested to enhance cognitive functions through GABA(A) receptor signaling by its metabolites. It has been shown that the level of pregnenolone is altered in certain brain areas of schizo...
Autores principales: | Wong, Peiyan, Chang, Cecilia Chin Roei, Marx, Christine E., Caron, Marc G., Wetsel, William C., Zhang, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519851/ https://www.ncbi.nlm.nih.gov/pubmed/23240026 http://dx.doi.org/10.1371/journal.pone.0051455 |
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