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IL-6 Is Not Necessary for the Regulation of Adipose Tissue Mitochondrial Content

BACKGROUND: Adipose tissue mitochondria have been implicated as key mediators of systemic metabolism. We have shown that IL-6 activates AMPK, a mediator of mitochondrial biogenesis, in adipose tissue; however, IL-6(−/−) mice fed a high fat diet have been reported to develop insulin resistance. These...

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Detalles Bibliográficos
Autores principales:	Wan, Zhongxiao, Perry, Christopher G. R., Macdonald, Tara, Chan, Catherine B., Holloway, Graham P., Wright, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519867/ https://www.ncbi.nlm.nih.gov/pubmed/23240005 http://dx.doi.org/10.1371/journal.pone.0051233

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