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Smac Mimetic SM-164 Potentiates APO2L/TRAIL- and Doxorubicin-Mediated Anticancer Activity in Human Hepatocellular Carcinoma Cells

BACKGROUND: The members of inhibitor of apoptosis proteins (IAPs) family are key negative regulators of apoptosis. Overexpression of IAPs are found in hepatocellular carcinoma (HCC), and can contribute to chemotherapy resistance and recurrence of HCC. Small-molecule Second mitochondria-derived activ...

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Detalles Bibliográficos
Autores principales:	Zhang, Shuijun, Li, Gongquan, Zhao, Yongfu, Liu, Guangzhi, Wang, Yu, Ma, Xiuxian, Li, Dexu, Wu, Yang, Lu, Jianfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519882/ https://www.ncbi.nlm.nih.gov/pubmed/23240027 http://dx.doi.org/10.1371/journal.pone.0051461

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