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Quercetin Potentiates Doxorubicin Mediated Antitumor Effects against Liver Cancer through p53/Bcl-xl

BACKGROUND: The dose-dependent toxicities of doxorubicin (DOX) limit its clinical applications, particularly in drug-resistant cancers, such as liver cancer. In this study, we investigated the role of quercetin on the antitumor effects of DOX on liver cancer cells and its ability to provide protecti...

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Detalles Bibliográficos
Autores principales: Wang, Guanyu, Zhang, Jiawei, Liu, Luying, Sharma, Sherven, Dong, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519886/
https://www.ncbi.nlm.nih.gov/pubmed/23240061
http://dx.doi.org/10.1371/journal.pone.0051764