Development of the Nanobody display technology to target lentiviral vectors to antigen-presenting cells

Lentiviral vectors (LVs) provide unique opportunities for the development of immunotherapeutic strategies, as they transduce a variety of cells in situ, including antigen-presenting cells (APCs). Engineering LVs to specifically transduce APCs is required to promote their translation towards the clin...

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Detalles Bibliográficos
Autores principales: Goyvaerts, C, De Groeve, K, Dingemans, J, Van Lint, S, Robays, L, Heirman, C, Reiser, J, Zhang, X-Y, Thielemans, K, De Baetselier, P, Raes, G, Breckpot, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520013/
https://www.ncbi.nlm.nih.gov/pubmed/22241177
http://dx.doi.org/10.1038/gt.2011.206

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