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Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species
Much attention has been devoted to neurodegenerative diseases involving redox processes. This review comprises an update involving redox processes reported in the considerable literature in recent years. The mechanism involves reactive oxygen species and oxidative stress, usually in the brain. There...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Bentham Science Publishers
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520039/ https://www.ncbi.nlm.nih.gov/pubmed/23730253 http://dx.doi.org/10.2174/157015912804143487 |
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author | Kovacic, Peter Somanathan, Ratnasamy |
author_facet | Kovacic, Peter Somanathan, Ratnasamy |
author_sort | Kovacic, Peter |
collection | PubMed |
description | Much attention has been devoted to neurodegenerative diseases involving redox processes. This review comprises an update involving redox processes reported in the considerable literature in recent years. The mechanism involves reactive oxygen species and oxidative stress, usually in the brain. There are many examples including Parkinson’s, Huntington’s, Alzheimer’s, prions, Down’s syndrome, ataxia, multiple sclerosis, Creutzfeldt-Jacob disease, amyotrophic lateral sclerosis, schizophrenia, and Tardive Dyskinesia. Evidence indicates a protective role for antioxidants, which may have clinical implications. A multifaceted approach to mode of action appears reasonable. |
format | Online Article Text |
id | pubmed-3520039 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Bentham Science Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-35200392013-06-01 Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species Kovacic, Peter Somanathan, Ratnasamy Curr Neuropharmacol Article Much attention has been devoted to neurodegenerative diseases involving redox processes. This review comprises an update involving redox processes reported in the considerable literature in recent years. The mechanism involves reactive oxygen species and oxidative stress, usually in the brain. There are many examples including Parkinson’s, Huntington’s, Alzheimer’s, prions, Down’s syndrome, ataxia, multiple sclerosis, Creutzfeldt-Jacob disease, amyotrophic lateral sclerosis, schizophrenia, and Tardive Dyskinesia. Evidence indicates a protective role for antioxidants, which may have clinical implications. A multifaceted approach to mode of action appears reasonable. Bentham Science Publishers 2012-12 2012-12 /pmc/articles/PMC3520039/ /pubmed/23730253 http://dx.doi.org/10.2174/157015912804143487 Text en ©2012 Bentham Science Publishers http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Kovacic, Peter Somanathan, Ratnasamy Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species |
title | Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species |
title_full | Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species |
title_fullStr | Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species |
title_full_unstemmed | Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species |
title_short | Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species |
title_sort | redox processes in neurodegenerative disease involving reactive oxygen species |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520039/ https://www.ncbi.nlm.nih.gov/pubmed/23730253 http://dx.doi.org/10.2174/157015912804143487 |
work_keys_str_mv | AT kovacicpeter redoxprocessesinneurodegenerativediseaseinvolvingreactiveoxygenspecies AT somanathanratnasamy redoxprocessesinneurodegenerativediseaseinvolvingreactiveoxygenspecies |