Cargando…

Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species

Much attention has been devoted to neurodegenerative diseases involving redox processes. This review comprises an update involving redox processes reported in the considerable literature in recent years. The mechanism involves reactive oxygen species and oxidative stress, usually in the brain. There...

Descripción completa

Detalles Bibliográficos
Autores principales: Kovacic, Peter, Somanathan, Ratnasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520039/
https://www.ncbi.nlm.nih.gov/pubmed/23730253
http://dx.doi.org/10.2174/157015912804143487
_version_ 1782252773287395328
author Kovacic, Peter
Somanathan, Ratnasamy
author_facet Kovacic, Peter
Somanathan, Ratnasamy
author_sort Kovacic, Peter
collection PubMed
description Much attention has been devoted to neurodegenerative diseases involving redox processes. This review comprises an update involving redox processes reported in the considerable literature in recent years. The mechanism involves reactive oxygen species and oxidative stress, usually in the brain. There are many examples including Parkinson’s, Huntington’s, Alzheimer’s, prions, Down’s syndrome, ataxia, multiple sclerosis, Creutzfeldt-Jacob disease, amyotrophic lateral sclerosis, schizophrenia, and Tardive Dyskinesia. Evidence indicates a protective role for antioxidants, which may have clinical implications. A multifaceted approach to mode of action appears reasonable.
format Online
Article
Text
id pubmed-3520039
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Bentham Science Publishers
record_format MEDLINE/PubMed
spelling pubmed-35200392013-06-01 Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species Kovacic, Peter Somanathan, Ratnasamy Curr Neuropharmacol Article Much attention has been devoted to neurodegenerative diseases involving redox processes. This review comprises an update involving redox processes reported in the considerable literature in recent years. The mechanism involves reactive oxygen species and oxidative stress, usually in the brain. There are many examples including Parkinson’s, Huntington’s, Alzheimer’s, prions, Down’s syndrome, ataxia, multiple sclerosis, Creutzfeldt-Jacob disease, amyotrophic lateral sclerosis, schizophrenia, and Tardive Dyskinesia. Evidence indicates a protective role for antioxidants, which may have clinical implications. A multifaceted approach to mode of action appears reasonable. Bentham Science Publishers 2012-12 2012-12 /pmc/articles/PMC3520039/ /pubmed/23730253 http://dx.doi.org/10.2174/157015912804143487 Text en ©2012 Bentham Science Publishers http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Kovacic, Peter
Somanathan, Ratnasamy
Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species
title Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species
title_full Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species
title_fullStr Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species
title_full_unstemmed Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species
title_short Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species
title_sort redox processes in neurodegenerative disease involving reactive oxygen species
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520039/
https://www.ncbi.nlm.nih.gov/pubmed/23730253
http://dx.doi.org/10.2174/157015912804143487
work_keys_str_mv AT kovacicpeter redoxprocessesinneurodegenerativediseaseinvolvingreactiveoxygenspecies
AT somanathanratnasamy redoxprocessesinneurodegenerativediseaseinvolvingreactiveoxygenspecies