Modulation of myocardial contraction by peroxynitrite

Peroxynitrite is a potent oxidant that is quickly emerging as a crucial modulator of myocardial function. This review will focus on the regulation of myocardial contraction by peroxynitrite during health and disease, with a specific emphasis on cardiomyocyte Ca(2+) handling, proposed signaling pathw...

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Detalles Bibliográficos
Autores principales: Kohr, Mark J., Roof, Steve R., Zweier, Jay L., Ziolo, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520483/
https://www.ncbi.nlm.nih.gov/pubmed/23248603
http://dx.doi.org/10.3389/fphys.2012.00468
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author Kohr, Mark J.
Roof, Steve R.
Zweier, Jay L.
Ziolo, Mark T.
author_facet Kohr, Mark J.
Roof, Steve R.
Zweier, Jay L.
Ziolo, Mark T.
author_sort Kohr, Mark J.
collection PubMed
description Peroxynitrite is a potent oxidant that is quickly emerging as a crucial modulator of myocardial function. This review will focus on the regulation of myocardial contraction by peroxynitrite during health and disease, with a specific emphasis on cardiomyocyte Ca(2+) handling, proposed signaling pathways, and protein end-targets.
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spelling pubmed-35204832012-12-17 Modulation of myocardial contraction by peroxynitrite Kohr, Mark J. Roof, Steve R. Zweier, Jay L. Ziolo, Mark T. Front Physiol Physiology Peroxynitrite is a potent oxidant that is quickly emerging as a crucial modulator of myocardial function. This review will focus on the regulation of myocardial contraction by peroxynitrite during health and disease, with a specific emphasis on cardiomyocyte Ca(2+) handling, proposed signaling pathways, and protein end-targets. Frontiers Media S.A. 2012-12-12 /pmc/articles/PMC3520483/ /pubmed/23248603 http://dx.doi.org/10.3389/fphys.2012.00468 Text en Copyright © 2012 Kohr, Roof, Zweier and Ziolo. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
spellingShingle Physiology
Kohr, Mark J.
Roof, Steve R.
Zweier, Jay L.
Ziolo, Mark T.
Modulation of myocardial contraction by peroxynitrite
title Modulation of myocardial contraction by peroxynitrite
title_full Modulation of myocardial contraction by peroxynitrite
title_fullStr Modulation of myocardial contraction by peroxynitrite
title_full_unstemmed Modulation of myocardial contraction by peroxynitrite
title_short Modulation of myocardial contraction by peroxynitrite
title_sort modulation of myocardial contraction by peroxynitrite
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520483/
https://www.ncbi.nlm.nih.gov/pubmed/23248603
http://dx.doi.org/10.3389/fphys.2012.00468
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