Unifocal Langerhans Cell Histiocytosis Simulating a Limbal Papilloma

PURPOSE: To report a rare presentation of unifocal Langerhans cell histiocytosis (LCH) simulating a limbal papilloma. CASE REPORT: A 24-year-old man presented with a limbal mass in his left eye which had initially been suspected to be a papilloma based on clinical findings. The mass was excised and a histopathological diagnosis of “acute bullous inflammation with granulation tissue” was made. The lesion relapsed 10 months later which necessitated repeat resection along with corneoscleral patch grafting. Histopathological studies of the excised lesion led to a final diagnosis of LCH. CONCLUSION: To the best of our knowledge, this is the second report of a rare presentation of LCH in the limbus which recurred after excision of the primary mass. The recurrent lesion was diagnosed based on histopathology and managed accordingly.