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Disease progression after R-CHOP treatment associated with the loss of CD20 antigen expression

A case of a follicular lymphoma transformed into a CD20(+) is described which progressed with the loss of CD20 expression after 8 cycles of R-CHOP. This phenomenon is not a rare event and has shown poor prognosis. Our purposes are to describe this event and suggest biopsy in relapsed or progressive...

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Detalles Bibliográficos
Autores principales: Bellesso, Marcelo, Xavier, Flavia Dias, Costa, Renata Oliveira, Pereira, Juliana, Siqueira, Sheila Aparecida Coelho, Chamone, Dalton Alencar Fischer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Hematologia e Hemoterapia 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520640/
https://www.ncbi.nlm.nih.gov/pubmed/23284263
http://dx.doi.org/10.5581/1516-8484.20110036
Descripción
Sumario:A case of a follicular lymphoma transformed into a CD20(+) is described which progressed with the loss of CD20 expression after 8 cycles of R-CHOP. This phenomenon is not a rare event and has shown poor prognosis. Our purposes are to describe this event and suggest biopsy in relapsed or progressive disease