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A randomized, double-blind, placebo-controlled phase 2 study evaluating the efficacy and safety of romiplostim treatment of patients with low or intermediate-1 risk myelodysplastic syndrome receiving lenalidomide
BACKGROUND: Lenalidomide treatment in myelodysplastic syndrome (MDS) may lead to thrombocytopenia and dose reductions/delays. This study evaluated the safety and tolerability of the thrombopoietin mimetic romiplostim and its effects on the incidence of clinically significant thrombocytopenic events...
Autores principales: | Wang, Eunice S, Lyons, Roger M, Larson, Richard A, Gandhi, Sunil, Liu, Delong, Matei, Carmen, Scott, Bart, Hu, Kuolung, Yang, Allen S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520696/ https://www.ncbi.nlm.nih.gov/pubmed/23190430 http://dx.doi.org/10.1186/1756-8722-5-71 |
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