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A novel, lactase-based selection and strain improvement strategy for recombinant protein expression in Kluyveromyces lactis

BACKGROUND: The Crabtree-negative yeast species Kluyveromyces lactis has been established as an attractive microbial expression system for recombinant proteins at industrial scale. Its LAC genes allow for utilization of the inexpensive sugar lactose as a sole source of carbon and energy. Lactose eff...

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Detalles Bibliográficos
Autores principales:	Krijger, Jorrit-Jan, Baumann, Jan, Wagner, Melanie, Schulze, Katja, Reinsch, Christian, Klose, Thomas, Onuma, Osita F, Simon, Claudia, Behrens, Sven-Erik, Breunig, Karin D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520740/ https://www.ncbi.nlm.nih.gov/pubmed/22905717 http://dx.doi.org/10.1186/1475-2859-11-112

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