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Pennogenin Tetraglycoside Induces Rat Myometrial Contraction and MLC20 Phosphorylation via PLC-IP(3) and RhoA/Rho Kinase Signaling Pathways

BACKGROUND: Total steroidal saponins extracted from the rhizome of Paris polyphylla Sm. var. yunnanensis (TSSPs) have been widely used in China for the treatment of abnormal uterine bleeding. We previously studied the main active constituents of TSSPs and their structure-activity relationships with...

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Detalles Bibliográficos
Autores principales:	Wang, Limei, Jia, Chao, Yu, Zuyin, Liu, Xiaolan, Kang, Liping, Cong, Yue, Shan, Yajun, Zhao, Zhenhu, Ma, Baiping, Cong, Yuwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520837/ https://www.ncbi.nlm.nih.gov/pubmed/23251567 http://dx.doi.org/10.1371/journal.pone.0051536

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