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Neuroprotective and Anti-Inflammatory Effects of the Flavonoid-Enriched Fraction AF4 in a Mouse Model of Hypoxic-Ischemic Brain Injury

We report here neuroprotective and anti-inflammatory effects of a flavonoid-enriched fraction isolated from the peel of Northern Spy apples (AF4) in a mouse of model of hypoxic-ischemic (HI) brain damage. Oral administration of AF4 (50 mg/kg, once daily for 3 days) prior to 50 min of HI completely p...

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Detalles Bibliográficos
Autores principales:	Keddy, Paul G. W., Dunlop, Kate, Warford, Jordan, Samson, Michel L., Jones, Quinton R. D., Rupasinghe, H. P. Vasantha, Robertson, George S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520852/ https://www.ncbi.nlm.nih.gov/pubmed/23251498 http://dx.doi.org/10.1371/journal.pone.0051324

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