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Structure analysis between the SWAP-70 RHO-GEF and the newly described PLD2-GEF
Small GTPases like Rac2 are crucial regulators of many cell functions central to life itself. Our laboratory has recently found that phospholipase D2 (PLD2) can act as a guanine nucleotide exchange factor (GEF) for Rac2. PLD2 has a Pleckstrin Homology (PH) domain but does not bear a Dbl homology (DH...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520882/ https://www.ncbi.nlm.nih.gov/pubmed/22858691 http://dx.doi.org/10.4161/sgtp.20887 |