Generation of a Genome Scale Lentiviral Vector Library for EF1α Promoter-Driven Expression of Human ORFs and Identification of Human Genes Affecting Viral Titer

The bottleneck in elucidating gene function through high-throughput gain-of-function genome screening is the limited availability of comprehensive libraries for gene overexpression. Lentiviral vectors are the most versatile and widely used vehicles for gene expression in mammalian cells. Lentiviral...

Descripción completa

Detalles Bibliográficos
Autores principales: Škalamera, Dubravka, Dahmer, Mareike, Purdon, Amy S., Wilson, Benjamin M., Ranall, Max V., Blumenthal, Antje, Gabrielli, Brian, Gonda, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520899/
https://www.ncbi.nlm.nih.gov/pubmed/23251614
http://dx.doi.org/10.1371/journal.pone.0051733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520899/
https://www.ncbi.nlm.nih.gov/pubmed/23251614
http://dx.doi.org/10.1371/journal.pone.0051733

Ejemplares similares